A heartbroken pensioner is being forced to watch her youngest daughter slowly die of a devastating genetic disease - which has already killed her husband and four other children.
Frances Culling's family has been wiped out by Huntington’s Disease which usually affects people after their mid-30s and causes a slow, distressing death.
Symptoms of the degenerative brain disorder usually include loss of muscle coordination, cognitive decline and dementia. There is no cure.
Mrs Culling's husband Alan died from the disease in 1975, seven years after developing symptoms - meaning it has been a constant presence in her life for 42 years.
It had already affected several members of his immediate family but was not present in Mrs Culling's, so each of their children should have had a 50-50 chance of remaining clear.
